Esimest korda kavatsen teha Sandmyer GABA to GHB sünteesi...mingeid nõuandeid ?

[methyllordir]

Tere toredad inimesed BB,

Nii et ma kavatsen teha mõned ghb läbi sandmyer reaktsiooni GABA ja Soduim nitriti, Mida te soovitate, et ma saaksin seda edukalt teha ?

Mul on kõik tavalised lahustid ja happed ja asjad + klaasid ja ma lähen selle toturialiga EW peale

 

[cancan]

How about it, did you succeed?

 

[CCL4 huffer]

keep the nitrous acid very cold and use a huge exess also for maximum yield set up a gas trap with bicarb and at the very end of the reaktion add the contents of the trap back in to not only neutralise but also squeese the last bits of GHB out.