Pomoč pri ekstrakciji psevdoefedrina 30 mg
- Thread starter OxycodoneHCL
- Start date
Zdravilo, ki ste ga opisali, je preveč nejasno, da bi natančno opisalo težavo, 200 miligramov ibuprofena in 30 miligramov PSE. Katere so še druge sestavine polnila? Ali gre za tablete ali tablete ali tekočine? Ali vsebuje zdravila, ki preprečujejo ekstrakcijo PSE?
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so naslednje neaktivne sestavine jedro tablete mikrokristalna celuloza kalcijev hidrogenfosfat brezvodni natrijev kroskarmelozni škrob koruzni škrob silicijev dioksid, koloidni brezvodni magnezijev stearat prevleka tablete hipromeloza makrogol 400 talk titanov dioksid (E171) rumeni železov oksid (E172)
so naslednje neaktivne sestavine jedro tablete mikrokristalna celuloza kalcijev hidrogenfosfat brezvodni natrijev kroskarmelozni škrob koruzni škrob silicijev dioksid, koloidni brezvodni magnezijev stearat prevleka tablete hipromeloza makrogol 400 talk titanov dioksid (E171) rumeni železov oksid (E172)
Neaktivne besede so bolj ali manj nepomembne - preprosto se bomo znebili celotne zmešnjave! Za ekstrakcijo psevdooblik lahko uporabite metanol ali IPA. To bo s seboj prineslo ibuprofen, ki bo predstavljal večino tistega, kar bo ostalo po filtriranju in izparevanju vaših ekstrakcij. Vse, kar moramo zdaj storiti, je preprosta ekstrakcija s hladno vodo. Ste že kdaj pripravili sok iz kodeina ali vicodina? Ista ideja...
Vzamemo vse in raztopimo v hladni vodi - poskusite ne porabiti toliko ali ravno prav veliko, ker boste morali pustiti, da se posuši, ali pa ga boste morali zmanjšati, odvisno od tega, kaj nameravate z njim početi naprej. Vsekakor jo raztopite v hladni vodi in jo položite v zamrzovalnik. Po približno 30 minutah, ko bo hladno, kolikor bo, in bo vse trdno padlo na dno, lahko raztopino odlijete in filtrirate - ločite ibuprofen od vode/pseudoraztopine. Pustite, da se posuši, ali pa nadaljujte s kuhanjem ...
Bodite previdni,
o7
Vzamemo vse in raztopimo v hladni vodi - poskusite ne porabiti toliko ali ravno prav veliko, ker boste morali pustiti, da se posuši, ali pa ga boste morali zmanjšati, odvisno od tega, kaj nameravate z njim početi naprej. Vsekakor jo raztopite v hladni vodi in jo položite v zamrzovalnik. Po približno 30 minutah, ko bo hladno, kolikor bo, in bo vse trdno padlo na dno, lahko raztopino odlijete in filtrirate - ločite ibuprofen od vode/pseudoraztopine. Pustite, da se posuši, ali pa nadaljujte s kuhanjem ...
Bodite previdni,
o7
- By OxycodoneHCL
Ko pravite, da je vse trdno, mislite, da bo psevdoefedrin izpadel, ibuprofen pa bo ostal raztopljen?
Ne, psevdo bo razpadel v alkoholu skupaj z nekaterimi drugimi stvarmi, večinoma z ibuprofenom. Najprej ga lahko ohladimo in večino dekantiramo. Nato filtriramo, malo speremo trdne snovi, da odstranimo vse, kar je morda ostalo, in se nato znebimo trdnih snovi. Prefiltrirana alkoholna raztopina, v kateri je naš psevdo. Glede na to, kako dobro smo filtrirali, lahko alkohol samo izpareva, če pa je bolj moten, ga za nekaj časa postavimo v zamrzovalnik (spet?) in morebitni ibuprofen se bo zbral na dnu. Poskusite filtrirati z bombažem v vratu lijaka namesto s kavnim(-i) filtrom(-i). Gravitacijski filter z bombažem filtrira zelo dobro, le da traja nekaj časa.
Uhh the inactive ingredients are the most important bit of information a person can have when extracting from pills. Using water on most pills nowadays will cause them to swell up and slowly release the active ingredient. Also the pills today can't just simply be ground to a powder and extracted with ethanol because of the matrix formulation of them. Meaning the shit holding onto the pseudoephedrine will still be holding onto it after a simple extraction. Doing an AB doesn't do anything either because the binder isn't bothered by pH. I don't know if it would crystalize correctly because of the binder, I doubt it though.
That binder/ polymer holding onto the pseudoephedrine needs to be dealt with before the pseudoephedrine is accessible and able to be reduced.
MCC is the first thing that pops out to me as the binder which causes it to swell. Also any pills that have a coating that is acting as a shell, like this pill, needs to be removed first. Otherwise it is going to just hinder what you're attempting to do.
Tetrachloroethylene might help you out.
The 3 types of matrix pills ("hydrophilic matrix" are also known as "dry matrix")
That binder/ polymer holding onto the pseudoephedrine needs to be dealt with before the pseudoephedrine is accessible and able to be reduced.
MCC is the first thing that pops out to me as the binder which causes it to swell. Also any pills that have a coating that is acting as a shell, like this pill, needs to be removed first. Otherwise it is going to just hinder what you're attempting to do.
Tetrachloroethylene might help you out.
The 3 types of matrix pills ("hydrophilic matrix" are also known as "dry matrix")
- Hydrophilic Matrix Tablets: These contain water-soluble polymers that swell in the presence of water, creating a gel layer that controls the drug release rate.
- Lipophilic Matrix Tablets: Made with water-insoluble polymers, these tablets release their contents by slowly eroding in the digestive tract.
- Bi-layer Matrix Tablets: These are composed of two layers with different release profiles, typically one immediate and one extended-release layer, allowing for dual drug release kinetics or fixed-dose combinations (two drugs in one tablet).