Cocaine is mischievous

FringGustavo

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It's a psychostimulant that isn't the most powerful, has a fairly short duration of effect and encourages continuous use.

It's less dopaminergic than many other stimulants, which are far less addictive - quite a paradox.

In my opinion, it's the worst stimulant when you take into account its benefits and drawbacks.
 

Paracelsus

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That's a really sharp take.

Cocaine works by blocking the reuptake of dopamine, norepinephrine, and serotonin—especially dopamine—in the nucleus accumbens, a core area involved in reward. But unlike amphetamines (which cause release of these neurotransmitters), cocaine just inhibits their reabsorption. That should, in theory, make it less intense than meth or even methylphenidate. But in practice, it's more addictive for a lot of people. Why?
  1. Short duration + rapid onset (especially when smoked as crack or injected): Effects hit fast and hard (especially smoked), but fade within 30–45 minutes. This creates a brutal craving–crash–repeat cycle.
  2. Psychological rollercoaster: The comedown from cocaine can feel sudden and emotionally raw—anxiety, dysphoria, paranoia. People re-dose just to stop that.
  3. Dopamine spikes vs. sustained elevation: Cocaine causes a sharp, short spike in dopamine. That rapid change may be more reinforcing than slower or sustained increases (like with Ritalin).
  4. Social & contextual factors: Cocaine is often used in binge patterns, in party or nightlife contexts. That social reinforcement strengthens the habit loop. It’s glamorized, expensive, and tied to specific identities—which also affects the psychology of use.
Addiction isn't just about raw dopamine levels—rate of onset, context, route of administration, neuroadaptation, and individual differences in neurobiology all matter. Some argue that the pattern and rhythm of stimulation (e.g., sharp peaks and valleys) might be more important than the total amount of dopamine.

So yes—paradoxical, but not irrational.

As for whether it's the best or the worst—that's ultimately a subjective judgment. With enough interest, anyone can find arguments both highlighting its appeal and exposing its itchiness.
 

SoldadoDeDrogas

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If you are buying some quality powder for an extended sniffing session with a close friend, that is one way to enjoy it. If you are scraping together your moms last $17 from the change jar for a $20 piece to smoke - it is quite a miserable way to exist if that is what motivates you. I can't seem to make sense or understand why people choose to live in poverty and depression just to experience these extremes at both ends, day after day. From the rush of intense euphoria and stimulation to a few moments later being paranoid, dysphoric, anxious and without money and craving more. After the initial novelty of the experience fades away there isn't much left. There are much better highs to experience at a much lower cost, and all around better things to do, even for a hedonist, but to each their own.
 
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