5c材料
①. Main ingredient, 1kg
②. dmf, 2.5-3 liters (68-12-2)
③. Potassium carbonate, 700g (584-08-7)
④. 5-Bromo-1-pentene , 514 g (1119-51-3)
Step:
Add ①②③ into the reaction flask, stir, heat to 60-70 degrees,
Slowly add ④, react for 2-3 hours, cool to room temperature
How to get the finished product:
1. Add the reaction solution into ice water while stirring, and add it slowly. The obtained powder is the finished product.
2. The reaction solution was extracted twice with dichloromethane and water, concentrated to dryness, added 1.5kg of ethanol, put in the refrigerator for 1-2 days, and a crystalline powder was obtained, which is the finished product.
The first kind of finished product is not as good as the second kind good.
equipment:
①. 50 liter reactor,
②. 20 liter rotary evaporator,
③. freezer,
④. Suction filter (centrifuge),
⑤. Extraction and crystallization barrels 60 liters, 4 pieces,
①. Main ingredient, 1kg
②. dmf, 2.5-3 liters (68-12-2)
③. Potassium carbonate, 700g (584-08-7)
④. 5-Bromo-1-pentene , 514 g (1119-51-3)
Step:
Add ①②③ into the reaction flask, stir, heat to 60-70 degrees,
Slowly add ④, react for 2-3 hours, cool to room temperature
How to get the finished product:
1. Add the reaction solution into ice water while stirring, and add it slowly. The obtained powder is the finished product.
2. The reaction solution was extracted twice with dichloromethane and water, concentrated to dryness, added 1.5kg of ethanol, put in the refrigerator for 1-2 days, and a crystalline powder was obtained, which is the finished product.
The first kind of finished product is not as good as the second kind good.
equipment:
①. 50 liter reactor,
②. 20 liter rotary evaporator,
③. freezer,
④. Suction filter (centrifuge),
⑤. Extraction and crystallization barrels 60 liters, 4 pieces,