Hi. The symptoms you're describing—severe nausea, excessive salivation, and vomiting upon initial use —are concerning and warrant attention.
Potential Causes of Your Symptoms
- Cannabinoid Hyperemesis Syndrome (CHS): This condition is characterized by cyclic episodes of nausea, vomiting, and abdominal pain in long-term cannabis users. While CHS is more commonly associated with natural cannabis, cases linked to synthetic cannabinoids have been reported. Notably, individuals with CHS often find temporary relief through hot showers or baths. Check my old article: http://bbzzzsvqcrqtki6umym6itiixfhn...hreads/cannabinoid-hyperemesis-syndrome.2186/
- Contamination with Toxic Substances: There have been instances where synthetic cannabinoids were adulterated with harmful substances like brodifacoum, a potent anticoagulant found in some rodenticides. Exposure can lead to severe bleeding disorders and other health complications
- Variable Potency and Composition: Noids can vary widely in their chemical makeup and strength. This unpredictability can result in unexpected and adverse reactions, especially if the product is more potent than anticipated.
Recommendations to Address and Prevent Symptoms
1. Cease Use: The most effective way to prevent these adverse reactions is to stop using synthetic cannabinoids. I understand that this is obvious, but I can’t help but write. Continued use, especially with unknown compositions, poses significant health risks.
If quitting entirely isn’t something you’re ready to do, at least
reduce your exposure to the most toxic part of your high:
- Skip the first cigarette: You mentioned the first one always hits hardest with nausea and salivation. Try starting with half a cig, or waiting longer between hits.
- Smoke less: The overwhelming nausea may be from a massive hit of a high-potency compound.
- Use in a safe space: Keep a calm environment, hydrate beforehand, and avoid smoking on an empty stomach.
2. Avoid Mixing or Smoking Unknown Blends: Synthetic blends are often contaminated. Some are sprayed unevenly, and some might even contain toxic chemicals.
- Avoid pre-rolled cigs or “gifted” blends from unreliable sources.
- If the batch smells strongly chemical, sweet, or metallic, toss it.
- If a new batch starts triggering worse symptoms than usual—stop immediately.
3. Manage the Vomiting When It Happens
- Hydrate with electrolytes: Vomiting can quickly lead to dehydration and worse effects next time you smoke.
- Use antiemetics (anti-nausea meds) like meclizine, ondansetron (Zofran, if accessible), or even ginger capsules—some users report mild relief.
4. Watch for Red Flags of Toxicity. Seek Medical Attention
If you notice any of the following,
stop using and get checked out ASAP:
- Gum bleeding, bruising easily, or blood in urine/stool (signs of anticoagulant poisoning)
- Confusion, seizures, or fainting
- Chest pain or trouble breathing
If you experience persistent or severe symptoms, it's crucial to consult a healthcare professional. They can assess for conditions like CHS or potential poisoning and provide appropriate treatment.